2018年结构生物学中的衍射方法戈登研究会议

[基本信息]

会议名称:2018年结构生物学中的衍射方法戈登研究会议

The 2018 Gordon Research Conference on Diffraction Methods in Structural Biology

所属学科:生物物理学、生物化学及分子生物学,细胞生物学

开始日期:2018-07-29

结束日期:2018-08-03

所在国家:美国

所在城市:美国

具体地点:美国 Lewiston, ME, US

主办单位:Gordon Research Conference

[会务组联系方式]

联系电话:401-783-4011

会议网站:https://www.grc.org/diffraction-methods-in-structural-biology-conference/2018/

[会议背景介绍]

This year the Diffraction Methods GRC will revisit and reassess the fundamentals of crystallography and the assumptions that lie behind them. The last few years have seen a rapid evolution in sources (FELs, diffraction limited synchrotrons, neutrons and electrons), detectors and data collection methods (serial/multi-crystal, room temperature) that has prompted a rethinking of how we should best collect and process data, especially the weak data that are now measurable with modern detectors. At this meeting, we will discuss the current state-of-the art in crystallography, including topics such as a) new and modified algorithms for data processing, structure solution and refinement, b) advances in detector technology and how data from these new detectors are best treated, c) new approaches to creating coordinate models (including refinement against unmerged data and the generation of models that describe structures undergoing progressive changes whether from radiation damage or a biologically relevant reaction), d) utilising perturbed datasets to fully characterise macromolecular crystals, and e) extracting more information from massive datasets.